I've never done it with a blend, but there's no reason why it wouldn't work. I think you should do it. I assume you're talking unflavored pipe tobacco, but if you are doing any flavors, heat and time will meld it all together. I recently did a 1% deerstongue blend. I was concerned about the fact that distributing it evenly through sliced plug would be difficult. I didn't kiln it, but I did put the jar in the crockpot, and that heat basically spread the deerstongue flavor through all of it. I also tried molasses on another blend, and it was gooey at first, but the heat of the crockpot helped it absorb all in.